Evidence-Based Supplement Research

Ingredient monographs, health topic guides, buying guides and third-party lab results from Mt. Angel Vitamins — a Highland Laboratories brand, family owned in Mt. Angel, Oregon since 1972.

All evidence-based supplement research

  • Vitamin D3 (Cholecalciferol) — Vitamin D3 (cholecalciferol) is the form of vitamin D your skin naturally produces from sunlight, and it is the most effective supplemental form for raising and maintaining healthy blood levels. Most adults, especially those living above the 37th parallel, do not get enough from sun and food alone.
  • NMN (β-Nicotinamide Mononucleotide) — NMN (β-nicotinamide mononucleotide) is a direct precursor to NAD+, the coenzyme your cells need for energy production, DNA repair, and essentially every metabolic process that keeps you alive and functioning. Supplementing with NMN has become one of the most researched approaches to supporting healthy NAD+ levels, which decline significantly with age.
  • Ashwagandha (Withania somnifera) — Ashwagandha (Withania somnifera) is the most clinically studied adaptogenic herb, with strong evidence for reducing cortisol, improving stress resilience, enhancing sleep quality, and supporting physical performance. Used in Ayurvedic medicine for over 3,000 years, it is now backed by modern randomized controlled trials showing measurable effects on both mental and physical stress markers.
  • Quercetin — Quercetin is a plant flavonoid with potent antioxidant, anti-inflammatory, and natural antihistamine properties, making it one of the most versatile supplements for immune support and seasonal allergy relief. Found naturally in onions, apples, and berries, supplemental quercetin delivers concentrated doses that food alone cannot match.
  • CoQ10 (Coenzyme Q10) — CoQ10 (coenzyme Q10) is a naturally occurring compound found in every cell in your body, where it plays an essential role in mitochondrial energy production and serves as a powerful lipid-soluble antioxidant. Your body's production of CoQ10 peaks around age 20 and declines steadily after that, making supplementation increasingly relevant as you age.
  • Urolithin A — Urolithin A is a postbiotic compound your gut bacteria make from the ellagitannins in pomegranates, walnuts, and berries, and it's the most-studied natural activator of mitophagy, your cells' system for clearing out worn-out mitochondria. The catch: most people's gut bacteria can't produce a meaningful amount, which is the entire reason direct supplementation exists.
  • The Complete Guide to Vitamin D — Vitamin D is both a nutrient and a hormone precursor that affects bone health, immune function, mood, muscle strength, and dozens of other body systems. This guide covers what the clinical evidence actually shows, who is most at risk for deficiency, how to test and supplement effectively, and how to cut through the noise around one of the most researched nutrients on the planet.
  • Immune Health — Build resilience with evidence-backed strategies